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Advanced topics in forensic DNA typing : methodology / John M. Butler

By: Material type: TextTextPublication details: Walthan, MA : Elsevier/Academic Press, c2012Description: xvii, 680 p. : ill. (some col.) ; 25 cmISBN:
  • 9780123745132
  • 0123745136
Subject(s): NLM classification:
  • W700
Contents:
Sample collection, storage, and characterization -- DNA extraction methods -- DNA quantitation -- PCR amplification: capabilities and cautions -- Short tandem repeat (STR) loci and kits -- Capillary electrophoresis: principles and instrumentation -- Quality assurance and validation -- DNA databases: uses and issues -- Missing persons and disaster victim identification efforts -- Degraded DNA -- Low-level DNA testing: issues, concerns, and solutions -- Single nucleotide polymorphisms and applications -- Y-chromosome DNA testing -- Mitochondrial DNA analysis -- X-chromosome analysis -- Non-human DNA -- New technologies and automation -- Legal aspects of DNA testing and the scientific expert in court
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Includes bibliographical references and index

Sample collection, storage, and characterization -- DNA extraction methods -- DNA quantitation -- PCR amplification: capabilities and cautions -- Short tandem repeat (STR) loci and kits -- Capillary electrophoresis: principles and instrumentation -- Quality assurance and validation -- DNA databases: uses and issues -- Missing persons and disaster victim identification efforts -- Degraded DNA -- Low-level DNA testing: issues, concerns, and solutions -- Single nucleotide polymorphisms and applications -- Y-chromosome DNA testing -- Mitochondrial DNA analysis -- X-chromosome analysis -- Non-human DNA -- New technologies and automation -- Legal aspects of DNA testing and the scientific expert in court

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